产品名称：Avelumab
中文名称：阿维鲁单抗
产品别称：MSB0010682
靶点：PDL1[Homo sapiens]
抗体亚型：IgG1 - lambda
来源：CHO cells
体内研究：在小鼠原位膀胱癌模型中，Avelumab能够减缓肿瘤生长并显著提高小鼠生存率[1]。
| Animal Model | 16 -18 weeks old Female C57BL/6 mice (bioluminescent orthotopic bladder cancer model) |
| Dosage | 400 µg on days 9, 12 and 15 |
| Result | significant (P<0.01) reduction in the average tumor volume of the avelumab-treated mice |
参考文献：1.Vandeveer AJ, Fallon JK, Tighe R, Sabzevari H, Schlom J, Greiner JW. Systemic Immunotherapy of Non-Muscle Invasive Mouse Bladder Cancer with Avelumab, an Anti-PD-L1 Immune Checkpoint Inhibitor. Cancer Immunol Res. 2016;4(5):452-462. doi:10.1158/2326-6066.CIR-15-0176
仅供科研使用
