产品名称：Gremubamab
中文名称：格瑞巴单抗
产品别称：MEDI3902
靶点：T3S & psl [Pseudomonas aeruginosa]
抗体亚型：IgG1
来源：CHO cells
体内研究：在兔血液和肺部感染模型中，Gremubamab可以预防和治疗严重的铜绿假单胞菌感染[1]。
| Animal Model | Rabbits(acute pneumonia model or bloodstream infection) |
| Dosage | 1, 5, 15 mg/kg |
| Result | Improved survival outcomes in a dose-dependent manner in a rabbit acute pneumonia model. |
参考文献：1.Le HN, Tran VG, Vu TTT, et al. Treatment Efficacy of MEDI3902 in Pseudomonas aeruginosa Bloodstream Infection and Acute Pneumonia Rabbit Models. Antimicrob Agents Chemother. 2019;63(8):e00710-19. Published 2019 Jul 25. doi:10.1128/AAC.00710-19
仅供科研使用
