产品名称：Tucotuzumab
中文名称：西莫白介素单抗
产品别称：huKS-IL2
靶点：EPCAM [Homo sapiens]
抗体亚型：IgG1 Kappa
来源：NS0 mouse myeloma cells
体内实验：在小鼠结肠腺癌模型中，Tucotuzumab可以抑制肿瘤生长，提高小鼠生存率[1]。
| Animal Model | Six to eight week old female Balb/c mice injected with CT26 |
| Dosage | total dose of 75 μg (Intratumoral injection) |
| Result | Resulted in significantly greater tumor growth suppression and enhanced survival. |
参考文献：Johnson EE, Yamane BH, Buhtoiarov IN, et al. Radiofrequency ablation combined with KS-IL2 immunocytokine (EMD 273066) results in an enhanced antitumor effect against murine colon adenocarcinoma. Clin Cancer Res. 2009;15(15):4875-4884. doi:10.1158/1078-0432.CCR-09-0110
仅供科研使用
